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۱Diagnostic Role of Fibrinogen Alone and in Combination with Lipids among Patients with Cardiovascular Disease
اطلاعات انتشار: World Applied Sciences Journal، بيست و هشتم،شماره۹، ۲۰۱۳، سال
تعداد صفحات: ۳
Inflammation plays an important role in the initiation, progression of atherosclerosis and subsequent development of atherosclerotic events. Elevated fibrinogen levels are considered as a risk factor for the development of atherosclerosis. The objectives of this study were first to evaluate the association between fibrinogen and cardiovascular disease and second to determine the role of combination of fibrinogen with lipid profile in the prognosis of cardiovascular disease. Two hundred patients were recruited for the study, of which hundred belongs to control and hundred were test group. For the entire study population fibrinogen and lipid profile were measured at the time of hospitalization. Among the patients with complication, there was a significant elevation in the levels of fibrinogen and lipid profile than the control. The results indicate that elevated plasma fibrinogen levels may be an independent risk factor for cardiovascular disease. It was found that a combination of measurement of fibrinogen with and total cholesterol or low–density lipoprotein cholesterol testing may prove to be even a better marker at risk response and this prognostic information may warrant closer monitoring and extra attention to modifiable cardiovascular risk factor.
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