توجه: محتویات این صفحه به صورت خودکار پردازش شده و مقاله‌های نویسندگانی با تشابه اسمی، همگی در بخش یکسان نمایش داده می‌شوند.
۱Development and Validation of a Reverse Phase HPLC Method for the Analysis of Ciprofloxacin and its Application in Bulk and Different Dosage Formulations (Text in Persian)
اطلاعات انتشار: World Applied Sciences Journal، سي و يكم،شماره۵، ۲۰۱۴، سال
تعداد صفحات: ۱۱
A new accurate، specific، precise، high performance liquid chromatographic (HPLC) method has been developed and validated for the determination of ciprofloxacin in bulk and in its pharmaceutical dosage forms of tablet and dry suspension. Acetonitrile: 0.25M Phosphoric Acid (pH 3.0 ± 0.1 with Diethylamine) (70:30)، was used as the mobile phase at a flow rate of 1.0 ml\min using a Symmetry C1 column. The effluent was spectrophotometrically monitored at 278 nm. The intraday and inter–day precisions showed coefficients of variation ranged from 0.51% to 1.18% at different levels of concentrations. The calibration curve was linear with a correlation coefficient of 0.99989. The averages of the absolute and relative recoveries were found to be 98.55% to 99.89%. The proposed HPLC method was successfully applied to quantify the amount of Ciprofloxacin in bulk and two dosage forms in quality control.
نمایش نتایج ۱ تا ۱ از میان ۱ نتیجه