توجه: محتویات این صفحه به صورت خودکار پردازش شده و مقاله‌های نویسندگانی با تشابه اسمی، همگی در بخش یکسان نمایش داده می‌شوند.
۱Mathematical simulation of behavior of sunflower oil extraction by supercritical carbon dioxide
نویسنده(ها): ، ، ،
اطلاعات انتشار: ششمین کنگره بین المللی مهندسی شیمی، سال
تعداد صفحات: ۴
In this research, oil extraction from sunflower seeds by supercritical carbon dioxide was simulated employing Shrinking Core Model inside a packed bed. Utilized operational conditions included; Temperature range of 313–343K, pressure range of 15–35 MPa, the particle size range of 0.1–3.0 mm and solvent flow rate 0.4–4.5 cm3\min. The developed model in this research considers four adjustable parameters namely the effective diffusion coefficient in the particles, Dep, mass transfer coefficient thru the bed and in a particle, Kf and Ks as well as, the axial dispersion coefficient, DL. Under aforementioned conditions the mass transfer coefficient thru the bed was determined to be 1.76– 3.75×10–8 m\s and axial dispersion coefficient was calculated to be 0.74–1.07×10–6 m2\s. From comparison of this model’s results and experimental data available in the literature, it was concluded that the shrinking core model predicts behavior of the sunflower oil extraction by supercritical fluid extraction (SFE) quite satisfactory. Ultimately, comparison the SFE model results and those obtained from the conventional Soxhlet method leads one to conclude that the amount of extraction in the former is much more than that of latter at a given time.<\div>

۲بررسی قدرت تمایز سروتیپ های سالمونلا با تکنیک PCR–Ribotyping در سویه های جداشده از کودکان مبتلا به اسهال زیر 15 سال
نویسنده(ها): ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ، ،
اطلاعات انتشار: مجله دانشگاه علوم پزشكي ايران، سال
تعداد صفحات: ۸

۳Effects of disulfiram on apoptosis in PANC–1 human pancreatic cancer cell line
اطلاعات انتشار: Research in Pharmaceutical Sciences، نهم،شماره۴(پياپي ۲۵)، ۲۰۱۴، سال
تعداد صفحات: ۸
Pancreatic carcinoma is currently considered as a rapidly progressive and fatal disease, and is typically diagnosed late in its natural course. It is characterized by a poor diagnosis and lack of response to conventional therapy. Recent studies have suggested that disulfiram (DSF), a member of the dithiocarbamate family, may have antitumor activity. This study aimed to evaluate the in vitro effect of DSF on apoptosis in human pancreatic cancerous cell line (PANC–1). PANC–1 cells were cultured and treated with DSF at doses of 5, 10, 13 µM for 24 h and apoptosis was measured. Methylation specific PCR (MS–PCR) and real–time quantitative PCR were carried out to detect the methylation pattern and to estimate the mRNA expression levels of RASSF1A, p21 and Bax. MS–PCR analysis demonstrated that no unmethylated band was apeared in PANC–1 cell line after DSF treatments. The real–time quantitative PCR results showed no significant mRNA expression for RASSF1A (p>0.05); whereas p21 and Bax expression were significantly (p0.01) enhanced after treatment with DSF. The results of the current study indicated that DSF can induce appoptosis in PANC–1 through p21 and Bax pathway but not through RASSF1A.
نمایش نتایج ۱ تا ۳ از میان ۳ نتیجه