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۱Change in Oxygen Absorption of Human Adult and Fetal Hemoglobin Due to 940 MHz Electromagnetic Field Radiation Exposure
اطلاعات انتشار: Biomacromolecular Journal، اول،شماره۲، Autumn ۲۰۱۵، سال
تعداد صفحات: ۹
The effects of electromagnetic fields (EMFs) radiation at the frequency of 940 MHz on the structure and function of human adult and fetal hemoglobin (HbA and HbF) were studied. After extraction and purification of HbA and HbF, the oxygen absorption values for exposed and unexposed HbA and HbF to EMF were compared. The slope of oxygen absorption curve for exposed HbA was increased while that for HbF was decreased compare to those before EMF exposing. Furthermore, the oxygen absorption saturation values were changed from 3.4–5.1 and from 5.1–3.1 mg l–1, respectively for HbA and HbF after exposing to EMF. The UV–Vis, circular dichroism and fluorescence spectroscopy confirmed the quaternary structural changes of both proteins after EMF exposure. So that, the structural transition of HbA from tense to relaxed state caused an increasing in oxygen absorption; whilst in HbF, transition from relaxed to tense state was occurred and therefore oxygen absorption was decreased.
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