توجه: محتویات این صفحه به صورت خودکار پردازش شده و مقاله‌های نویسندگانی با تشابه اسمی، همگی در بخش یکسان نمایش داده می‌شوند.
۱Inverse Miniemulsion Method for Synthesis of Gelatin Nanoparticles in Presence of CDI\NHS as a Non–toxic Cross–linking System
نویسنده(ها): ، ،
اطلاعات انتشار: Journal of Nano Structures، چهارم،شماره۳، ۲۰۱۴، سال
تعداد صفحات: ۹
In this research، gelatin nanoparticles were synthesized via inverse miniemulsion method by employing a mixture of a water soluble carbodiimide (CDI) and N–hydroxysuccinimide (NHS) as a non–toxic cross–linking system. The gelatin nanoparticles were characterized for their size and size distribution، morphology and stability and were compared with those of nanoparticles cross–linked by glutaraldehyde (GA) as the most commonly utilized cross–linking agent. The results showed theformation of more homogeneous nanoparticles with smaller size when CDI\NHS used as cross–linking agent under the same synthesis condition. Moreover، dilute solution viscosimetry experiments confirmed the stability of the nanoparticles under various physicochemical conditions. The differences in the characteristics of CDI\NHS and GA cross–linked nanoparticles were ascribed to the different nature of network formation using the two cross–linking agents. Generally، these results suggested CDI\NHS cross–linked gelatin nanoprticles as an interesting candidate for drug delivery application.
نمایش نتایج ۱ تا ۱ از میان ۱ نتیجه