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۱Some Histological Changes in Thoracic Aorta Associated with Laser Therapy in Experimentally Hypertensive Rats
اطلاعات انتشار: World Applied Sciences Journal، سي و سوم،شماره۱۲، ۲۰۱۵، سال
تعداد صفحات: ۵
The aim of the present study is to investigate the possible histological changes following laser therapy in the thoracic aorta of rats subjected to experimentally hypertensions. Studies were conducted on 35 adult female albino rats; five rats were served as a normal healthy control group. The remaining 30 rats were subjected to experimental induction of hypertension and divided into two equal groups (15 rats each) as treated and untreated subgroups. Hypertension was induced by daily oral administration of L– NAME (50 mg\kg b.w) for one month. A tail cuff was used to measure blood pressure, Laser Therapy used, for a total of 16 minutes, each acupoint received 4 minutes (3 time \ week). After 1.5 and 3 months from treatment, rats were anesthetized with light ether, sacrificed and heart and aorta were dissected out, fixed in 10% formal saline for 24 hours, histologically processed and examined. Results revealed significant (P0.05) decrease in blood pressure in rats treated with laser and became near normal. Microscopic examination of aorta showed intima with little endothelial cell drop and media smooth muscle cells proliferated with uniform thickness and regular arrangement. In conclusion, treatment with laser has favorable effect on blood pressure without deleterious effect on histological changes of thoracic aorta in rats.
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