توجه: محتویات این صفحه به صورت خودکار پردازش شده و مقاله‌های نویسندگانی با تشابه اسمی، همگی در بخش یکسان نمایش داده می‌شوند.
۱Serum anti–cyclic citrullinated peptide antibodies before and after treatment by disease–modifying anti–rheumatic drugs
اطلاعات انتشار: Chronic Diseases Journal، دوم،شماره۲، ۲۰۱۴، سال
تعداد صفحات: ۶
BACKGROUND: Rheumatoid arthritis (RA) is the most common chronic disease involving joints. Anti–cyclic citrullinated peptide (anti–CCP) as a specific antibody is a reliable index to early diagnosis of RA. Disease–modifying anti–rheumatic drugs (DMARDs) can reduce progression of RA joint destruction. The present study aimed to investigate the effects of DMARDs in reducing serum anti–CCP.METHODS: A cross–sectional study was performed on 30 patients including 22 females and 8 males RA patients according to the American College of Rheumatology (ACR) classification criteria, who referred to the Rheumatology Clinic. Treatment with DMARD group started at the beginning of the study (May 2009). At 1st and 6th month of the study, clinical findings and disease activities were recorded and anti–CCP was measured.RESULTS: At the beginning and the end of the study, morning stiffness for more than 1 h and involvement of three areas were, 28 (93%) and 12 (40%), respectively. Indicators of disease severity in patients, the mean ± SD serum levels of erythrocyte sedimentation rate at the beginning and end, were 40.7 (30–59) mm\1 h and 13.4 (9–86) respectively. Anti–CCP at the beginning and end of the study was 141.83 (65.8–101.09) U\ml and 65.8 (62–92) U\ml respectively (P 0.05). Disease Activity Score in 28 joints and rheumatoid factor positive and C–reactive protein positive were significantly different at the onset and at the end of the study (P 0.05).CONCLUSION: Measurement of serum anti–CCP is a helpful index of treatment response and monitoring of treatment efficacy in patients with RA.

۲Prevalence of internet addiction among university students in Ilam: a cross–sectional study
اطلاعات انتشار: International Journal of Epidemiologic Research، اول،شماره۱، ۲۰۱۴، سال
تعداد صفحات: ۷
Background and aims: Internet addiction is one of the problems emerged with the development of technology. Considering the potential negative effects of internet addiction on health, the present study aimed to determine the prevalence of internet addiction in university students in Ilam, west of Iran, in 2014. Methods:In this cross– sectional study, 1066 university students in both public and private sectors were assessed in 2014. The samples were selected by multi–stage random sampling method. Data were collected by a two–part questionnaire: the personal characteristics and Internet Addiction Test (IAT)–20. This 20–itemed questionnaire measures internet addiction in mild, moderate and severe levels. Each answer is scored based on a Likert scale from 1 to 5. The higher score represents a greater level of addiction. The total score between 20 and 49 represented mild, 50–79 showed moderate and 80–100 was severe addiction. Results:Overall, 466 (43.7%) of students were placed in the Internet addiction group. Generally, 39.6% of students had mild and 4.1% had moderate addiction. No case of sever Internet addiction was seen. Prevalence of internet addiction in the medical students was higher compared to nonmedical students (P 0.0001). Conclusion:Based on the results, internet addiction should be considered as a serious problem in adolescents and young adults. So, it is necessary that proper use of internet to be educated to adolescents and young adults to prevent the risk of internet addiction.

۳Risk factors of pelvic organ prolapse in Iranian women: a cross–sectional study
اطلاعات انتشار: International Journal of Epidemiologic Research، اول،شماره۱، ۲۰۱۴، سال
تعداد صفحات: ۶
Background and aims: Pelvic organ prolapse (POP) is a common condition which affects on a large proportion of women. The objective of this study was to determine the risk factors of POP in Iranian women. Methods: This cross–sectional study was carried out to examine the role of demographic, anthropometric and clinical characteristics in POP disease in a sample of 365 females in Ilam, Iran. Examinations were performed according to Pelvic Organ Prolapse Quantification (POPQ) technique in dorsal lithotomic position. Then, the sample divided into two groups as with and without prolapse. Then, unilabiate and multivariate analyses were performed. Results: Totally, 365 women participated in this study. The prevalence of POP was 80.8%. Univariate logistic regression analysis showed a significant differences between groups with and without POP based on age, maximum birth weight, BMI, pregnancy, delivery mode, delivery operative and delivery position. But after multivariate analysis, the most significant factors identified as risk factors for POP were age (OR= 1.12, 95% CI= 1.02–1.23, P= 0.02), normal vaginal delivery (NVD; OR= 6.18, 95% CI= 1.43–26.75, P= 0.01) and episiotomy (OR= 30, 95% CI= 5.69–158.11, P= 0.000). Conclusion: Findings of the study showed that several risk factors could collaborate in creating of POP. However; body mass index and number of pregnancies are modifiable factors. So, maternal care providers should educate women for maintaining the ideal weight and decreasing the number of pregnancy in order to prevent POP.

۴The global trend of infertility: an original review and meta–analysis
اطلاعات انتشار: International Journal of Epidemiologic Research، اول،شماره۱، ۲۰۱۴، سال
تعداد صفحات: ۹
Background and aims: Infertility is one of the most important conditions in reproductive system and there is no reliable estimates for global prevalence of infertility. Therefore, knowing the prevalence of infertility is important and can be effective in decision making. Methods: We systematically reviewed all published papers in Medline database and Scopus (1988–2010). Univariate and multivariate approaches were applied to assess the causes of heterogeneity among the selected studies. Meta–regression was used to examine the relationship between the prevalence of infertility and the year of study. Data manipulation and statistical analyses were performed using Stata 11.1. Results: The study population was not similar in all papers. Studies evaluated the prevalence of infertility in the general population, the total female population, women and couples. Some studies defined infertility as failure to conceive within 12 months of regular sexual life without contraception methods while other studies defined it as failure to conceive within 24 months of regular sexual life without contraception methods. Overall, 52 studies met our inclusion criteria and the pooled worldwide of infertility was obtained about 10%. The correlation between prevalence of secondary infertility and year of study was significant (P=0.039). Conclusions: Approximately 10% of the world''s population suffers from infertility. Due to the negative impact of infertility on couples in various aspects of life, and the need for treatment and support programs, accurate estimate of infertility is essential worldwide.

۵General health status among high school students in Ilam: a cross–sectional study
اطلاعات انتشار: International Journal of Epidemiologic Research، دوم،شماره۱، ۲۰۱۵، سال
تعداد صفحات: ۶
Background and aims: Many factors could affect on the health status. This study aimed to assess the general health status of high–school students in Ilam province in 2014. Methods:This cross– sectional study determined the general health status of high–school students in Ilam, located in west of Iran in 2014. The samples were selected by multi–stage random sampling method. Data were collected by a two–part questionnaire. The first part of the questionnaire included the personal characteristics and the second part of the questionnaire contained General Health Questionnaire– 28 (GHQ–28. Results: A total of 381 students were enrolled in this study. Overall 236 (61.9%) of students had healthy status. In addition, 145 (38.1%) of all participants had disorder in one or more dimensions of their general health status. The mean±SD of overall score of general health was 5.78±4.53 in healthy status students and 7.83±5.72 in disorder status students. The difference in overall score of general health was statistically significant between healthy and disorder status students (P0.001). Moreover, the differences in the age, school grade, parental education and number of children living with families were significant between healthy and disorder status students (P0.05). Conclusion: General health is an important issue among adolescents and high–school students who are at high risk of general health disorder. Therefore, the regular evaluation of their general health status is necessary for planning an appropriate counseling program.

۶Predictive factors for infertility of women: a univariate and multivariate logistic regression analysis
اطلاعات انتشار: International Journal of Epidemiologic Research، دوم،شماره۱، ۲۰۱۵، سال
تعداد صفحات: ۸
Background and aims: Infertility is a major problem during reproductive age. Physical and psychological effects of infertility in women are problematic. The aim of this study was to determine the potential predictive factors of infertility, among women referring both public and private health centers in Ilam province, western Iran, in 2013. Methods: In this cross–sectional study, 1013 women referring the health care centers of Ilam province were enrolled in 2013. The participants were selected by simple random sampling method and their demographic, medical and obstetric variables were collected. The univariate and multiple logistic regression analyses were used to predict the potential risk factors of infertility. Results: The husband’s education and occupation showed to be suitable independent predictor variables for infertility by multivariate logistic regression analysis (OR: 1.36 and 2, respectively). Overall percentage of correct classification of the model was 88.7%. It means that, considering the husband’s education and women’s occupation, the ability of the model to predict the actual category of the cases was 88.7%. Conclusions: It seems that husband education level and women occupation are independent predictive variables. The women at risk of infertility have to be identified and high–quality counseling should be given in order to minimize the complications of infertility in both genders.

۷The factors influencing on knowledge, attitudes, and practices in women with breast cancer referring to health centers of Ilam in 2013
اطلاعات انتشار: International Journal of Epidemiologic Research، دوم،شماره۳، ۲۰۱۵، سال
تعداد صفحات: ۶
Background& Aims: The mortality rate for breast cancer is directly related to the stage of disease at diagnosis. The present study aimed to determine the influencing factors on knowledge, attitudes, and practices of women regarding breast cancer and its screening methods.Material & Methods: In a cross– sectional study, evaluated 383 women referring health centers of Ilam. Sampling was done in two stages. The inclusion criteria were included healthy women with least literate. Data was collected by a two part questionnaire including demographic characteristics and knowledge, attitudes and practices of women regarding breast cancer and its screening methods. Data were analyzed by chi–square and t–test in SPSS–16 software and a significance level of 0.05.Results: The Mean ± SD knowledge score was 22.43 ± 11.01. The Mean ± SD attitude and performance score were 29.08 ± 3.34 and 3.52 ± 1.66 respectively. There was a significant correlation between age, occupation and education with knowledge, attitude and practice of women about breast cancer and its screening methods (P 0.05). There wasn’t a significant relationship between the marital status, history of benign breast disease and family history with knowledge, attitudes and practices about breast cancer and screening methods, (P> 0.05). Conclusion: However, half of the participants had good knowledge about breast cancer and screening procedures, but also, all participants with good knowledge hadn’t good practice. Therefore, it is necessary further training to enhance awareness and more research to identifying barriers to women's performance.

۸Health related quality of life in the female–headed households
نویسنده(ها): ، ،
اطلاعات انتشار: International Journal of Epidemiologic Research، دوم،شماره۴، ۲۰۱۵، سال
تعداد صفحات: ۶
Background and aims: According to psychological research female–headed households have a lot of physical and mental problems because they experience stress and anxiety more than the other women in general population. The aim of this study was to determine the quality of life and the associated factors in female–headed households under the Welfare Organization coverage of Ilam Province.Methods: In this descriptive analytical study, 787 female–headed households under the Welfare Organization coverage of Ilam in urban and rural in Ilam province participated in this study. Systematic random sampling was used as a sampling method. A validated questionnaire (SF–36) completed in a six–month interval and then the data were collected and analyzed.Results: From 787 female–headed households contributing to the project, the numbers of missing subjects were 79 and 708 of the subjects completed the questionnaires (response rate 89.9%). Mean ± SD age of participants was 53.3±19.18. The results of this study showed an unfavorable health related quality of life in female–headed households spatially in role–physical (mean score 48.06) and mental health (mean score 40.80) demission. We found that having the chronic disease and living in rural area were associated with an unfavorable health related quality of life (P≤0.001).Conclusion: According to the results, the most important reason affecting the quality of life in female–headed households is low level of illiteracy and having a chronic illness.

۹Extraction and measurement of the Quercetin flavonoid of Prosopis farcta in Khouzestan climatic condition
اطلاعات انتشار: Advanced Herbal Medicine، اول،شماره۱، ۲۰۱۴، سال
تعداد صفحات: ۷
Background and aims: Medicinal plants are a valuable resource for flavonoids extraction. Prosopis fracta is one of the plants with medicinal properties. Prosopis fracta was found in abundance in southern regions in Iran. Coersetin is medicinal substance found in the fruit of this plant. Quercetin is used in treatment of cancer and viral infections. This study was conducted to determine the Quercetin flavonoid in Prosopis fracta samples in different regions of Khuzestan. Methods: The Prosopis fracta fruit collected from different regions of Khuzestan (Susangerd, Ahvaz, Abadan, Mollasani, Behbahan and Ramhormoz). The beads were isolated from the fruit. Shell and the flesh were dried in an Oven. The dried materials were mixed and flavonoids extracted with a suitable solvent. The extract was injected into the High Performance Liquid Chromatography (HPLC) system. Then, the compound, Quercetin quantity and standard peak in each sample have been determined. Results: Based on the results, the Susangerd samples (0.0033 mg\ml) and Abadan (0.0008 mg\ml) have maximum and minimum levels of Quercetin flavonoid, respectively. Conclusions: Quercetin flavonoid extracted from Prosopis farcta fruits of Susangerd is richer than other regions of Khuzestan province. Therefore, it is recommended to use the Prosopis fracta fruit grown in Susangerd for extraction of the Quercetin flavonoid.

۱۰The measurement of the quercetin of different parts of Tribulus terrestris by HPLC
اطلاعات انتشار: Advanced Herbal Medicine، اول،شماره۳، ۲۰۱۵، سال
تعداد صفحات: ۶
Background and aims: Tribulus terrestris fruit, leaf, and root have medical effects in the treatment of cancer, viral infections and prevention of cardiovascular diseases. The present study was aimed to evaluate the quercetin flavonoid levels from different parts of the Tribulus terrestris collected from different regions of Khuzestan in 2014. Methods: In this experimental study, four parts of the Tribulus terrestris including; fruits, leaves, stems and roots were collected from different regions of Khuzestan including Shushtar, Mollasani and Andimeshk. The analysis was carried out to compare the chemical profile of the different extracts of Tribulus terrorists using reverse phase HPLC with UV detector. The mobile phase that consisted of phosphoric acid buffer with pH=3 and acetonitrile was used for isocratic elution. The flow rate was adjusted to 1.0 ml\min. The detection wavelength was at 203 nm. All separations were performed at ambient temperature. Results: The results reported that the quercetin flavonoid level were highest in the Andimeshk leaves samples (69.57427 ppm). However, the Andimeshk fruits samples (4.141953 ppm) have the lowest levels of the quercetin flavonoid. Conclusion: Considering the cost effectiveness in extracting compounds from medicinal plants, it is recommended to identify the highest level of the quercetin flavonoid in each region and in each part of the plant.

۱۱Predictors of Recurrent Febrile Seizures in Iranian Children
نویسنده(ها): ، ،
اطلاعات انتشار: Zahedan Journal of Research in Medical Sciences، ۲۰۱۳، سال
تعداد صفحات: ۵
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