توجه: محتویات این صفحه به صورت خودکار پردازش شده و مقاله‌های نویسندگانی با تشابه اسمی، همگی در بخش یکسان نمایش داده می‌شوند.
۱Correlation of plasma interleukin–18 concentration and severity of renal involvement and disease activity in systemic lupus erythematosus
اطلاعات انتشار: Journal of nephropathology، پنجم،شماره۱، Jan ۲۰۱۶، سال
تعداد صفحات: ۶
Background: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by activation of T and polyclonal B lymphocytes. IL–18 was originally identified as a factor which enhances IFN–γ production and is a potent inducer of the inflammatory mediators by T cells, causing severe inflammatory disorders in SLE. Objectives: This study aimed to evaluate the association of plasma interlukine–18 (IL–18) concentration and severity of lupus nephritis (LN) and disease activity in SLE patients.Patients and Methods: In this cross–sectional study, 113 patients with SLE and 50 healthy individuals were examined. Serum level of IL–18 was measured. The severity and activity of the disease was determined by Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) score. The severity of kidney involvement was studied by renal biopsy, serum creatinine and 24 hours urine protein level. Results: The mean level of serum IL–18 was significantly higher in the patients than controls (577.67 ± 649.95 versus 60.48 ± 19.53 pg\ml; P 0.001). In SLE patients with active disease level of serum IL–18 was significantly higher than chronic disease (622.77 ± 716.54 versus 182 ± 184.37 pg\ml; P 0.001). The serum level of IL–18 was significantly higher in stage IV (P 0.001) and V (P 0.001) of patients with LN, than other stages. Conclusions: The current study showed that the serum IL–18 is significantly higher in the patients than controls and it significantly correlated with sever renal involvement and disease activity in SLE patients.

۲Thermo–Elastic Damping in Nano–beam Resonators Based on Nonlocal Theory
اطلاعات انتشار: International Journal of Engineering، بيست و ششم،شماره۱۲، December۲۰۱۳ ، سال
تعداد صفحات: ۱۰
In this article thermoelastic damping in nano–beam resonators is investigated based on nonlocal theory of elasticity and the Euler–Bernoulli beam assumptions. The governing equation of deflection of the beam is obtained from shear and moment resultants and stress–strain relationship of the nonlocal elasticity model and also the governing equations of thermoelastic damping are established by using, two dimensional non–Fourier heat conduction with one relaxation time based on continuum theory frame. Free vibration of the nano–beam resonators is analyzed using Galerkin reduced order model formulation for the first mode of vibration. In the present investigation a clamped–clamped nano–beam with isothermal boundary conditions at both ends is studied. This nonlocal nano–beam model incorporates the length scale parameter (nonlocal parameter) which can capture the small scale effect. The obtained results are compared with the numerical results of the classical thermoelastic models. Thermoelastic damping effects on the damping ratio are studied for the various nano–beam thicknesses and ambient temperatures. In addition to, the study includes computations for different values of nonlocal theory parameter. The results show that with increasing the amount of nonlocal parameter and also with decreasing the length of the nano–beam, difference of the results of classical and nonlocal theory increases.

۳Mechanical Response of a Piezoelectrically Sandwiched Nano–Beam Based on the Non–Local Theory
اطلاعات انتشار: International Journal of Engineering، بيست و ششم،شماره۱۲، December۲۰۱۳ ، سال
تعداد صفحات: ۱۰
This article deals with the mechanical analysis of a fixed–fixed nano–beam based on nonlocal elasticity theory. The nano–beam is sandwiched with two piezoelectric layers through it’s upper and lower sides. The electromechanical coupled equations governing the problem are derived based nonlocal theory considering to Euler–Bernoulli beam assumptions and based on the nonlocal piezoelectricity according to the electrostatic Maxwell’s equations. Two piezoelectric voltages are employed to tune the stiffness of the nano–beam. The obtained equations are solved by step by step linearization method and Galerkin’s weighted residual method. The obtained results are compared with the results of the local model, and also the effect of piezoelectric voltages on the non–locality of the model is investigated.
نمایش نتایج ۱ تا ۳ از میان ۳ نتیجه