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۱Novel Potentiometric Determination of Torasemide for Antidoping Purpose, Using β–Cyclodextrin and Calixarene
اطلاعات انتشار: Analytical & Bioanalytical Electrochemistry، چهارم،شماره۴، Aug ۲۰۱۲، سال
تعداد صفحات: ۱۵
Two novel Torasemide (TOR) sensors were investigated, using β–cyclodextrin and calix[4]arene as ionophores, where linear responses within concentration ranges of (10–7 10–2 and 10–8–10–2M) and Nernstian slopes of (58.77 and 59.214 mV\decade) over the pH range of 7–12 were obtained, respectively.The selectivity coefficients of the developed sensors indicate excellent selectivity for TOR, where the second sensor shows a higher sensitivity if compared to the first one. The proposed fabricated sensors display useful analytical characteristics for the determination of TOR (for anti–doping purpose) in bulk powder, biological fluids and in pharmaceutical formulation.
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