توجه: محتویات این صفحه به صورت خودکار پردازش شده و مقاله‌های نویسندگانی با تشابه اسمی، همگی در بخش یکسان نمایش داده می‌شوند.
۱Numerical solution of Volterra integral equation of the ¯rst kind of any ¯nite dimension by Block Pulse Functions
نویسنده(ها):
اطلاعات انتشار: همایش ملی پژوهشهای کاربردی در علوم و مهندسی، سال
تعداد صفحات: ۱۱
In this paper n–dimension Block Pulse Functions and their prop–erties are introduced. Then we show how to use them to solve n–dimensionVolterra integral equation of the ¯rst kind. After that we talk about error bound of numerical solutions and convergence and test our method by some numerical examples.<\div>

۲Evaluation of anticonvulsant effect of two novels 4–[1–(4–fluorobenzyl) –5–imidazolyl] dihydropyridine derivatives in mice
نویسنده(ها): ، ، ، ،
اطلاعات انتشار: Research in Pharmaceutical Sciences، هشتم،شماره۲(پياپي ۱۹)، ۲۰۱۳، سال
تعداد صفحات: ۵
In this study the anticonvulsant effect of two dihydropyridine derivatives [diethyl –1,4– dihydro –2,6– dimethyl –4–(4– fluoro benzyl–2– methylthio –5– imidazolyl)–3,5– pyridine dicarboxilat (A) and diethyl –1,4– dihydro –2,6– diethyl –4–(4– fluoro benzyl–2– methylthio –5– imidazolyl)–3,5– pyridine dicarboxilat (B)] by pentylenetetrazole (PTZ) and electroshock in mice was evaluated. The latency and HLTE (hind limb tonic extensions), the duration of HLTE and the mortality protection in pentylenetetrazole test and the HLTE duration in electroshock test were assessed. Both compounds had significant differences with negative control in all doses used. There was no significant difference between nifedipine and B (96.7 and 169.2 mg\kg doses) in the starting point of HLTE and between nifedipine and A (62.2 and 108.9 mg\kg doses) in the duration of HLTE in the PTZ test. Also, there was no significant difference between nifedipine and B (96.7 and 169.2 mg\kg doses) and A (62.2 and 108.9 mg\kg doses) in electroshock test. All doses of A and B and nifedipine showed less effect than phenytoin and valproate. This study showed that both A and B have anticonvulsant activity in the PTZ–induced seizure model and the MES test. These compounds, thus, might be useful in the petit mal and grand mal epilepsy.
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