توجه: محتویات این صفحه به صورت خودکار پردازش شده و مقاله‌های نویسندگانی با تشابه اسمی، همگی در بخش یکسان نمایش داده می‌شوند.
۱MORALITY AND BIOLOGY
نویسنده(ها): ،
اطلاعات انتشار: کنگره بین المللی اخلاق زیستی، سال
تعداد صفحات: ۵
What is morality? The concept of morality assumes different meaning and value for individuals, at times becoming synonymous with religion, sympathy, virtue, or other equally terms. In recent years, scientist have acquired a unique voice in the ongoing debate of human morality. Biologist often turn to the past, reaching for the origin of morality , to elucidate its elucidate its mystery. Their arguments incite heated debate. Indeed, a scientific explanation for morality forces humans to evaluate their self–image as a species . yet it must be asked how, and to what extent, biology helps us understand what morality is and how it has evolved? Can one fully explain man’s inclination moral sentiment with science? The sheer duration and intensity of the debate regarding morality proves that there are no clear answer. To truly gain a heightened understanding of this amibiguous and highly charged concept, it is most useful to consider not only biological factors, but social , cultural , and psychological influences as well. An interdisciplinary exploration , a union rather than a separation, of various of various fields, is indispensable

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۲In Silico Analysis of Amino acid Substitutions in DNA gyrase subunit A
اطلاعات انتشار: Journal of Applied Biotechnology Reports، اول،شماره۳، Summer ۲۰۱۴، سال
تعداد صفحات: ۴
The broad consumption of antibiotics such as fluoroquinolones and the genetic adaption of opportunistic pathogenic bacteria including Pseudomonas aeruginosa, has led to develop of floroquinolone–resistant strains of Pseudomonas aeruginosa. Thus, the aim of the present study is to reveal the types of hot spot mutations occurring in selected DNA gyrase subunit A gene in fluoroquinolone–resistant Pseudomonas aeruginosa strains. For this purpose, 70 fluoroquinolone–resistant partial cds genes of Pseudomonas aeruginosa TOHO strains (P12–P377) for DNA gyrase subunit A have been aligned with wild genes for DNA gyrase subunit A by BLAST program and multiple alignment, to detect probable gyrA mutations. Based on analyses hot spot mutations including Thr–83→Ile (92.44%), Ile–83→Thr (1.33%), Asn–87→Asp (0.44%) existing as single and Thr–83→Ile & Asn–87→Asp (5.78%) as double substitutions were detected. According to this survey, the point mutations in DNA gyrase subunit A gene need more consideration about fluroquinolone–resistant Pseudomonas aeruginosa isolates. The strains with hot spot SNP mutations may rise a huge concern from epidemiologic aspect for antibiotic therapy treatment.
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