توجه: محتویات این صفحه به صورت خودکار پردازش شده و مقاله‌های نویسندگانی با تشابه اسمی، همگی در بخش یکسان نمایش داده می‌شوند.
۱Preparation of Combined Inactivated Vaccine Against Salmonella enteritidis, Salmonella typhimurium and Clostridium perfringens type A and C Toxins
اطلاعات انتشار: World Applied Sciences Journal، سي و سوم،شماره۳، ۲۰۱۵، سال
تعداد صفحات: ۷
This study was planned to prepare and evaluate the immunizing and protective efficacy of aninactivated combined vaccine containing S. enteritidis, S. typhimuriumbacterins and C. perfringens type A and C toxoids. According to the type of adjuvant used, two vaccine formulations were investigated; one of them was adjuvanted with mineral oil and the other with Nigella sativa oil. Three groups of chickens (80 chicks\group) were vaccinated twice S\C. The first group was vaccinated with the mineral oil adjuvanted vaccine, the second group was vaccinated with the N. sativaadjuvanted vaccine and the third group was kept unvaccinated as control group. Blood samples were collected weekly and humeral immune response was measured against Salmonellabacterins using ELISA and against C. perfringens toxoids using SNT. The prepared vaccines induced significantly high protection rates in challenge test using virulent Salmonellastrains and significant clearance of S. enteritidis and S. typhimurium from blood and internal organs of the immunized chickens. Also fecal shedding was significantly reduced. The protection level against C. perfringens types A and C was greatly increased. The N. sativa oil adjuvanted formulation stimulated significantly higher protective efficacy as compared with mineral oil adjuvant.
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