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۱Influence of Local Application of Immunomodulator Cycloferon on the Clinical Course of Chronic Odontogenic Maxillary Sinusitis
اطلاعات انتشار: World Applied Sciences Journal، سي ام،شماره۱۰، ۲۰۱۴، سال
تعداد صفحات: ۴
94 subjects aged from 23 to 54 years with diagnosis of «Chronic odontogenic maxillary sinusitis, oro–antral fistula» were under the supervision in the period from 2008 to 2013. During the comprehensivetreatment of these patients clinical and immunological parameterswere analyzed as well as the effectiveness of local immunotherapy by cycloferon. Based on the obtained results it was concluded that signs of adverse clinical course and outcome of the disease were detected in patients suffering from chronic odontogenic maxillary sinusitis for more than two months. It was concluded that adding cycloferon to conventional treatment makes postoperative course of chronic odontogenic maxillary sinusitis more favorable in comparison with a control group of patients. The most pronounced positive effect of cycloferon can be observed in patients with lingering course of chronic process, while its effectiveness is lower in patients with continuous course that raises the prospect of finding more adequate and more effective immunotherapy in this pathology.
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