توجه: محتویات این صفحه به صورت خودکار پردازش شده و مقاله‌های نویسندگانی با تشابه اسمی، همگی در بخش یکسان نمایش داده می‌شوند.
۱Preparation and Characterization of Starch Nanoparticles Contaning Curcumin for Antibacterial Effect by Precipitation and Ionic Gelation Method
نویسنده(ها): ، ، ،
اطلاعات انتشار: پانزدهمین کنگره ملی مهندسی شیمی ایران، سال
تعداد صفحات: ۵
The objective of our study is to load antibacterial, polyphenolic drug, curcumin in starch nanoparticles inorder to enhance bioavailability and to reduce bacterial activity effectiveness in dental caries. Starch was dissolved in distilled water. Drug in ethanolic solution at various concentrations with different volumes of ethanol was added dropwise to above starch solution kept over magnetic stirrer at 70°c for a period of one hour. Followed by sonication for 15 min. The resulting Starch nanoparticles suspension was centrifuged at 15,000 rpm for 15 min. After freeze drying the Nanoparticles were collected. results show that formulation No: 5 having optimum nanosized particles. It shows good encapsulation efficiency. And From all these results it concludes that formulation No 5 is the best formulation and which is recommended for future studies like Nano dry powder preparation and interaction with oral bacteria especially Streptococcus mutans<\div>

۲Curcumin Encapsulated in Chitosan Nanoparticles: Preparation, Optimization, Characterization, and Antimicrobial Study on Dental Caries
نویسنده(ها): ، ، ،
اطلاعات انتشار: کنفرانس بین المللی یافته های نوین پژوهشی در شیمی و مهندسی شیمی، سال
تعداد صفحات: ۹
Curcumin was loaded onto chitosan nanoparticles by using precipitation and ionic gelation method. Curcumin loaded chitosan nanoparticles exhibited enhanced solubility in aqueous solution as compared to free curcumin. Effects of formulation parameters such as curcumin concentrations and different volumes of ethanolic solution were found to affect the particle size and loading efficiency (LF) of the curcumin loaded chitosan nanoparticles. Under optimum conditions, curcumin loaded chitosan nanoparticles with mean particles size of 66.3 nm and maximum loading efficiency of 11.9% were achieved. Curcumin was observed to release out from chitosan nanoparticles in a sustained way under physiological pH over a period of 96 hours. From these results it concludes that formulation No 1 is the best formulation and which is recommended for future studies like Nano dry powder preparation and interaction with oral bacteria especially Streptococcus mutans.<\div>
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