مقالههای Mohammad Reza Jafari
توجه: محتویات این صفحه به صورت خودکار پردازش شده و مقالههای نویسندگانی با تشابه اسمی، همگی در بخش یکسان نمایش داده میشوند.
۱Correlation of plasma interleukin–18 concentration and severity of renal involvement and disease activity in systemic lupus erythematosus
اطلاعات انتشار: Journal of nephropathology، پنجم،شماره۱، Jan ۲۰۱۶، سال ۰
تعداد صفحات: ۶
Background: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by activation of T and polyclonal B lymphocytes. IL–18 was originally identified as a factor which enhances IFN–γ production and is a potent inducer of the inflammatory mediators by T cells, causing severe inflammatory disorders in SLE. Objectives: This study aimed to evaluate the association of plasma interlukine–18 (IL–18) concentration and severity of lupus nephritis (LN) and disease activity in SLE patients.Patients and Methods: In this cross–sectional study, 113 patients with SLE and 50 healthy individuals were examined. Serum level of IL–18 was measured. The severity and activity of the disease was determined by Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) score. The severity of kidney involvement was studied by renal biopsy, serum creatinine and 24 hours urine protein level. Results: The mean level of serum IL–18 was significantly higher in the patients than controls (577.67 ± 649.95 versus 60.48 ± 19.53 pg\ml; P 0.001). In SLE patients with active disease level of serum IL–18 was significantly higher than chronic disease (622.77 ± 716.54 versus 182 ± 184.37 pg\ml; P 0.001). The serum level of IL–18 was significantly higher in stage IV (P 0.001) and V (P 0.001) of patients with LN, than other stages. Conclusions: The current study showed that the serum IL–18 is significantly higher in the patients than controls and it significantly correlated with sever renal involvement and disease activity in SLE patients.
۲Geochemistry of Oxygen and Carbon Stable Isotopes in Non–Sulfide Zn–Pb Deposits, Case Study: Chah–Talkh non–Sulfide Zn–PbDeposit (Sirjan– South of Iran)
اطلاعات انتشار: World Applied Sciences Journal، بيست و چهارم،شماره۹، ۲۰۱۳، سال ۰
تعداد صفحات: ۹
The study of isotopic ratios of oxygen and carbon has gained importance to determine the origin of ore bearing fluids, carbon origin and also to determine the formation temperature of non sulfide lead and zinc minerals. In order to determine the origin of fluids and carbon existing in zinc carbonate minerals in Chah–Talkh deposit, initially the amounts of changes of 18O and 13C in various zinc minerals in important deposits SMOW PDB of Iran and the world were studied and then by comparing these values in Chah–Talkh deposit with other deposits, the origin of fluids responsible for the ore forming, carbon and formation temperature of Chah–Talkh deposit was determined. The range of changes of 18O in smithsonite mineral in non sulfide lead and SMOW zinc deposits varies from 18.3 to 31.6 per mil and 18O in hydrozincite mineral varies from 7.8 to 27 per mil. SMOW Due to the impossibility of smithsonite sampling from Chah–Talkh deposit (due to being fine–grained and dispersed), hydrozincite minerals which have high isotopic similarities with smithsonite are used for isotopic analysis of carbon and oxygen. The range of changes of 18O in hydrozincite mineral of Chah–Talkh deposit SMOW varies from 7.8 to 15.15 per mil which places in the domain of metamorphic water. The extensiveness of 18O changes in Chah–Talkh indicates the role of at least two fluids in the formation of nonsulfide minerals. SMOW The formation temperature of non–sulfide minerals (hydrozincite) in Chah–Talkh deposit is obtained at 70 to 85°C which indicates the role of metamorphic fluids in the formation of deposit. Complete weathering of sulfide minerals to a depth of 134 meters confirms the role of rising metamorphic fluids in the formation of nonsulfide minerals. The 13C values of Chah–Talkh deposit are set in the range of atmospheric CO and carbonate rocks PDB 2 which the existence of atmospheric CO2 indicates the role of atmospheric fluids and the existence of carbonate carbon–rock is indicative of the role of metamorphic fluids in the precipitation of nonsulfide Zn minerals.
اطلاعات انتشار: World Applied Sciences Journal، بيست و هفتم،شماره۱۱، ۲۰۱۳، سال ۰
تعداد صفحات: ۵
Florin deposits are one of rare elements of resources in the world in recent years. The aim of this study is a preliminary geochemical exploration on rare elements by one, two and multivariate statistical methods. Results show rare elements are independent to Pb and Ag. Additionally, there is a positive relationship among the rare elements and also rare elements increasing are inversion relationships with Pb veins in the mine.
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